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Megaspore Biotic
  • Megaspore Biotic
  • Megaspore Biotic
  • Megaspore Biotic
  • Megaspore Biotic
Megaspore Biotic

Microbiome Labs

Megaspore Biotic

MegaSporeBiotic by Microbiome Labs is a 100% spore-based, broad-spectrum probiotic shown to maintain healthy gut barrier function. It combines five Bacillus strains that have been shown to maintain healthy gut barrier and immune function.

  • Five Bacillus strains: B. subtilis HU58™, B. indicus HU36™, B. clausii SC-109, B. coagulans SC-208 and B. licheniformis SL-307.
  • Gut reconditioning: Promotes microbial diversity and helps maintain key health-promoting, commensal gut bacteria.
  • No refrigeration needed: Does not require refrigeration; store in a cool, dry place.

Free shipping on orders over $75

Third-party tested for purity

Physician formulated

Directions

Start with 1/2 capsule or 1 full capsule with food and slowly increase to 2 capsules per day using the following protocol.
01
Week 1
1 capsule every other day
02
Week 2
1 capsule daily
03
Week 3+
2 capsules daily
If 1 capsule every other day causes side effects, try starting with 1/2 capsules or even 1/4 capsule in some cases. Possible side effects may include abdominal cramping, loose stools, and changes in bowel movements. Though these side effects may be uncomfortable, they are a sign that the product is working! Side effects should resolve within 2-3 days.
Additional Info

Form/Duration
Study Details and Results
Reference
Total Gut Restoration
in vitro (M-SHIME®)
Fecal samples were used in vitro to evaluate the effects on the gut microbiome using the Total Gut Restoration supplementation system. TGR supplementation resulted in short-chain fatty acids (SCFAs) production and supported intestinal barrier function and immune function.
DOI: 10.2217/fmb-2022-0066
MegaSporeBiotic™ and MegaMucosa™
The combination of MegaSpore™ and MegaMucosa™ promoted immune function and provided support to colonic mucosa.
DOI: 10.3390/nu12123607
MegaSporeBiotic™
10 days
300 million CFU of MegaSporeBiotic™ supplementation supported immune function and iron levels in mice.
DOI: 10.1002/jpen.1851
MegaSporeBiotic™
12 weeks
12 weeks of supplementation with MegaSporeBiotic™ supported triglyceride levels in study subjects.
PMID: 33041703
MegaSporeBiotic™
Administration of MegaSporeBiotic™ was shown to support liver function.
DOI: 10.3390/nu12030632
MegaSporeBiotic™
60 days
MegaSporeBiotic™ provided relief for occasional abdominal discomfort and supported elimination and digestive health in study subjects.
DOI: 10.3390/nu11091968
MegaSporeBiotic™
30 days
MegaSporeBiotic™ demonstrated cardiac-supportive and immune-supportive properties.
DOI: 10.4291/wjgp.v8.i3.117
MegaSporeBiotic™ and MegaPre™
MegaSporeBiotic™ and MegaPre™ promoted microbial diversity in the transverse and descending colon. Additionally, this synbiotic combination promoted the production of all SCFAs in the gut, including acetate, propionate, and butyrate.
DOI: 10.1016/j.ijpx.2019.100021
MegaSporeBiotic™
3 weeks
MegaSporeBiotic promoted bacterial diversity and supported ammonia, propionate, and lactate levels.
DOI: 10.1016/j.foodres.2021.110676
MegaSporeBiotic™ and antibiotics
MegaSporeBiotic™ was shown to support immune system health and help maintain normal intestinal flora.
DOI: 10.3390/microorganisms10061178
Warning

Take at least 2-3 hours before or after antibiotics; do not use with clindamycin or in immune-compromised conditions.

Disclaimer

Consult your healthcare professional before use if pregnant, nursing, taking medications, or for any use by minors. Do not use if safety seal is broken or missing. KEEP OUT OF REACH OF CHILDREN. The products on this site have not been evaluated by the Food and Drug Administration. They are not intended to diagnose, treat, cure, or prevent any disease. Consult a licensed health care professional before beginning, changing or stopping any supplementation regimen.

Casey Kelley, MD, ABoIM

Why we chose this

Your gut is home to a huge community of bacteria. MegaSpore is a spore-based probiotic with five Bacillus strains that helps maintain healthy gut barrier function. I like that it doesn't need refrigeration, just a cool, dry place. And it's two capsules once a day, so it's easy to build into a patient's routine.

Casey Kelley, MD, ABoIM

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